genetic risk variants
Nasopharyngeal Carcinoma Risk Genes Identified, Characterized
Using association, regulatory, and functional analyses coupled with cell line experiments, researchers characterized new nasopharyngeal cancer risk genes.
Hand Condition Contributors Include Variants Passed Down From Neanderthals
Researchers identified dozens of variants associated with Dupuytren's disease, nicknamed "Viking disease," including three risk variants originating in Neanderthal sequences.
Consortium Produces Pangenome Reference Spanning Dozens of Chinese Populations
Researchers put together a pangenome reference with high-quality, haplotype-phased genome assemblies for individuals from minority and majority populations in China.
Prostate Cancer Study Suggests High Performance of Polygenic Risk Score Based on Small Variant Set
A 269-variant multi-ancestry polygenic risk score performed as well as genome-wide scores when it came to predicting prostate cancer in men of African or European ancestry.
GWAS Links Human Voice Pitch to Gene Influencing Cardiovascular, Hormonal Processes
A genome-wide association study on Icelanders led to variants in ABCC9, which encodes a regulatory subunit of a potassium channel.