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Applied BioCode Fungal Panel Assay

Applied BioCode said this week that it has launched a Fungal Panel Assay for research use only. The assay detects the most common agents of invasive fungal infections, especially in lower respiratory samples. They include Aspergillus, Rhizopus, Mucor, Rhizomucor, Cunninghamella, Lomentospora, Fusarium, Cryptococcus, Pneumocystis jirovecii, and dimorphic pathogens (Coccidioides immitis/posadasii, Histoplasma capsulatum, and Blastomyces dermatiditis). The assay is designed to run primarily on the company's BioCode MDx-3000 multiplex PCR system and is intended for infectious disease research or pharmaceutical development.

The Scan

Cystatin C Plays Role in Immunosuppression, Cancer Immunotherapy Failure, Study Finds

A study in Cell Genomics provides insight into how glucocorticoids can lead to cancer immunotherapy failure via cystatin C production.

Aging, Species Lifespan Gene Expression Signatures Overlap

An Osaka Metropolitan University team reports in Nucleic Acids Research that transcriptional signatures of aging and maximum lifespan have similarities.

Splicing Subgroup Provides Protocols for Evaluating Splicing Variant Data

The group presents their approach on how to apply evidence codes to splicing predictions and other data in the American Journal of Human Genetics.

Single-Cell Transcriptomic Atlas of Mouse Cochlea to Aid Treatment Development

Researchers in PNAS conducted single-cell and single-nuclear sequencing of about 120,000 cells at three key timepoints in cochlear development to generate a transcriptomic atlas.