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RealSeq Biosciences Selective Suppression Probe

RealSeq Biosciences has launched its Selective Suppression Probe (SSP), a targeted probe to deplete undesired or overabundant species from RNA samples. SSP provides increased reads and up to ten times the sequencing depth for small RNAs or micro RNAs of interest. It can be used with both single- and paired-end sequencing and on a variety of sequencing platforms. The product includes a standard probe set for human plasma samples as well as customizable probes for individual research needs.

The Scan

Cystatin C Plays Role in Immunosuppression, Cancer Immunotherapy Failure, Study Finds

A study in Cell Genomics provides insight into how glucocorticoids can lead to cancer immunotherapy failure via cystatin C production.

Aging, Species Lifespan Gene Expression Signatures Overlap

An Osaka Metropolitan University team reports in Nucleic Acids Research that transcriptional signatures of aging and maximum lifespan have similarities.

Splicing Subgroup Provides Protocols for Evaluating Splicing Variant Data

The group presents their approach on how to apply evidence codes to splicing predictions and other data in the American Journal of Human Genetics.

Single-Cell Transcriptomic Atlas of Mouse Cochlea to Aid Treatment Development

Researchers in PNAS conducted single-cell and single-nuclear sequencing of about 120,000 cells at three key timepoints in cochlear development to generate a transcriptomic atlas.