Skip to main content
Premium Trial:

Request an Annual Quote

Tempus xR Sequencing Assay

Tempus launched a new standalone RNA next-generation sequencing assay this week, dubbed Tempus xR, which covers clinically relevant fusions in more than 100 targeted genes, as well as altered splicing for MET Exon 14 and EGFRvIII. The test falls under the firm's existing standard of whole-genome and exome sequencing, but Tempus described xR as a new option for physicians that are specifically interested in RNA fusions or altered splicing, as well as providers, researchers, and biopharma companies seeking RNA sequencing analysis of existing samples. According to the company, the launch will divide its current operations, with its xT assay now providing DNA sequencing and xR offering RNA sequencing for clinical and research use.

The Scan

Cystatin C Plays Role in Immunosuppression, Cancer Immunotherapy Failure, Study Finds

A study in Cell Genomics provides insight into how glucocorticoids can lead to cancer immunotherapy failure via cystatin C production.

Aging, Species Lifespan Gene Expression Signatures Overlap

An Osaka Metropolitan University team reports in Nucleic Acids Research that transcriptional signatures of aging and maximum lifespan have similarities.

Splicing Subgroup Provides Protocols for Evaluating Splicing Variant Data

The group presents their approach on how to apply evidence codes to splicing predictions and other data in the American Journal of Human Genetics.

Single-Cell Transcriptomic Atlas of Mouse Cochlea to Aid Treatment Development

Researchers in PNAS conducted single-cell and single-nuclear sequencing of about 120,000 cells at three key timepoints in cochlear development to generate a transcriptomic atlas.