gene regulation
Space Travel Shifts White Blood Cell Expression in Transcriptomic Study
Researchers saw immune-related gene expression changes in astronauts on the International Space Station, along with shifts to baseline in the weeks after their return to Earth.
Nasopharyngeal Carcinoma Risk Genes Identified, Characterized
Using association, regulatory, and functional analyses coupled with cell line experiments, researchers characterized new nasopharyngeal cancer risk genes.
Human-Specific Features Found With CRISPR Screening on Stem Cells
With loss-of-function screens on human, chimp, and orangutan stem cells, researchers narrowed in on species-specific genetic dependencies involving dozens of genes.
Heart Disease Risk Variants, Genes Found in GWAS Meta-Analysis
Researchers identified 16 loci associated with a heart condition that is overrepresented in young women, leading to distinct genes and pathways.
Blood Pressure Genetic Variants Linked to Regulatory Functions, Cardiovascular Pathways
Using massively parallel reporter assays and other approaches, researchers explored the functional effects of blood pressure-associated variants and narrowed in on causal variants.